Who We Are

KidneyCAN is a patient-created and patient-driven movement, drawing energy and motivation from people all over the United States and the world whose lives are impacted by kidney cancer.

Our mission is to accelerate cures for kidney cancer by:

  • advocating for government and industry funding,
  • facilitating collaboration across research and clinical disciplines,
  • offering direct financial support for researchers with promising ideas,
  • engaging the patients and caregivers through educational outreach, and
  • connecting patients with trial and treatment opportunities.

Read about Our 2025 Impact:

The mission of KidneyCAN is to accelerate cures for kidney cancer. We believe that means accelerating cures for everyone through a commitment to practices that promote equity, diversity, and inclusion.

Our Story

KidneyCAN was formed by kidney cancer patients, survivors, and caregivers who originally met through the Smart Patients forum. Recognizing the lack of critical research funding dollars, the KidneyCAN founders wanted to provide a means of stimulating research progress through advocacy and direct fundraising. In short, we provide a voice for the kidney cancer community as we work to accelerate cures.

Our Founders

Bryan Lewis

CEO & Co-Founder
Bryan has been an active legislative advocate and policy spokesman for the kidney cancer community in Washington, D.C., and across the U.S. for the past 6 years. In 2017, he was successful in spearheading the efforts to obtain $10 million for the inaugural Kidney Cancer Research Program (KCRP) pursuant to the Congressionally Directed Medical Research Programs (CDMRP.org).

While in Washington, Bryan was the Vice President, Operations & General Counsel for Brand USA, directing the day-to-day operations of the organization where he oversaw the legal matters, human resources, finance, accounting, events and information technology departments and assisted with the development of the organization’s long-term strategy and objectives.

Prior to joining Brand USA, Bryan served as Chief of Staff & General Counsel for the U.S. Travel Association, a Washington, D.C.-based trade association. Bryan was directly involved in the planning and support efforts for the passage of the Travel Promotion Act. He also had responsibilities for setting up and managing the association’s political action committee (Travel PAC).

A native of North Carolina, he earned his undergraduate degree in political science at Gordon College in Massachusetts and his law degree from Boston College. He is admitted to the bar in Massachusetts and the District of Columbia. Bryan is a multi-year kidney cancer survivor. He and his family reside in Philadelphia, PA.

Bryan founded the Kidney Cancer Action Network (KCAN) in 2017 and subsequently merged with the Kidney Cancer Coalition in 2019 to form KidneyCAN.

External Committee Involvement

  • NCI (National Cancer Institute) Renal Task Force (NIH) (2020-present)
  • NCCN Guidelines Panel- Kidney Cancer, Patient Advocate (2018-present)
  • EAB- External Advisory Board, Patient Advocate,  Kidney Cancer Research Consortium (KCRP) (2019-present)
  • Inaugural Vision Setting Committee, Kidney Cancer Research Program, CDMRP/KCRP – FY2017
  • ASCO mRCC Guidelines Panel (2019-2020)
  • One Voice Against Cancer (OVAC) Coalition Member (2016-present)
  • Defense Health Research Consortium, (DHRC) representative
  • International Kidney Cancer Coalition (IKCC), Vice Chair (2019-present)
  • Kidney Cancer Research Summit (KCRS) Executive Steering Committee (2018-present)
  • Patient Advocates Forum on the Concept of a Cure in Cancer (PAF3C), Patient Advocate (2026)

 

Brenda Knapp

Treasurer & Co-Founder
Brenda is a certified public accountant with over 25 years in public accounting where she has been an advisor to a wide variety of non-profit organizations. Her range of services to non-profits over the years have included preparing 990’s, preparing audited and reviewed financial statements and consulting.

In addition to her professional experience with non-profits, she has served on numerous charitable organization boards over the past 17 years. Her responsibilities have included all executive board positions, chairing fundraising events, and serving on numerous committees.

Brenda graduated with a BS degree in Accounting from Christopher Newport University in 1988.

Brenda together with her husband Ralph, founded the Kidney Cancer Coalition in 2016 and subsequently merged their non-profit with KCAN to form KidneyCAN in 2019.

Ralph Knapp

Co-Founder
Ralph Knapp was the owner of Action Paving & Construction in Virginia Beach, VA. He started his company many years ago at the age of 24, and the company has grown to over 45 employees. Ralph was an avid golfer and loved the outdoors.

In 2014, at the age of 53, Ralph was diagnosed with stage IV renal cell carcinoma – kidney cancer. He battled kidney cancer valiantly and became committed to not only raising awareness but much-needed research dollars for an underfunded cancer.

In 2015, Ralph and his wife Brenda raised over $300,000 to fund the RADVAX clinical trial for 25 advanced kidney cancer patients. Enrollment began spring of 2017 at the University of Texas, Southwestern in Dallas. The principal investigator was Hans Hammers, MD, PhD.

Brenda and Ralph founded the Kidney Cancer Coalition in 2016 and subsequently merged their non-profit with KCAN to form KidneyCAN in 2019. Ralph lived in Virginia Beach and Florida with his wife, Brenda, until his death in March of 2022.

Ralph brought a unique energy and entrepreneurial acumen to kidney cancer advocacy, and despite his health challenges, was never without a smile and a hug for everyone. He was a model of faith and optimism, and our team will miss him enormously.

We are committed to carrying Ralph’s mission forward and hope you’ll read more about his life and work.

Board of Directors

TONI CHOUEIRI, M.D.

DIRECTOR

Dr. Toni K. Choueiri is the Director of the Lank Center for Genitourinary (GU) Oncology at Dana-Farber Cancer Institute (DFCI)/Brigham and Women’s Hospital and the Jerome and Nancy Kohlberg Chair and Professor of Medicine at Harvard Medical School. He is the Co-leader of the Kidney Cancer Program at Dana-Farber/Harvard Cancer Center and past President of the Medical Staff at DFCI (2016-2018). He is the recipient of the George Canellos Award for Excellence in Clinical Investigation and Patient Care from DFCI and the Eugene P. Schonfeld Award from the Kidney Cancer Association (KCA). He serves on the National Comprehensive Cancer Network (NCCN) Kidney Cancer Panel, the National Cancer Institute (NCI) GU Steering Committee, and is past Chairman (2015-2018) of the Medical and Scientific Steering Committee of the KCA. In addition, he is an Aresty Scholar from the Wharton School of Business at the University of Pennsylvania.

Dr. Choueiri is interested in developing novel experimental therapies and biomarkers in GU malignancies, including renal cell carcinoma (RCC). His research also focuses on the epidemiology, diagnosis, and treatment outcomes of GU cancers, especially through having co-established the International Metastatic RCC Database Consortium criteria for RCC risk stratification. His biomarker work has shed light on complex immunogenomics mechanisms contributing to response and resistance to targeted therapy and immunotherapy. He has also contributed to understanding of the underlying biology and rationale for therapies in rare histological variants of RCC such as papillary and sarcomatoid RCC.

Dr. Choueiri has received research funding from the NCI, the Department of Defense (DOD), the American Society of Clinical Oncology (ASCO), and industry partners. His work has been published in journals such as the NEJM, Nature, Nature Medicine, Science, Cancer Cell, Journal of American Medical Association (JAMA), JAMA Oncology, The Lancet, Lancet Oncology, and Journal of Clinical Oncology. He lectures frequently throughout the United States and around the world. He has over 600 PubMed-indexed publications and is the lead investigator of multiple national and international phase I-III clinical trials in GU cancers.

Leah Christoforidis

Leah Christoforidis

DIRECTOR

Leah Christoforidis is the General Counsel at Red Chalk Group, LLC, with more than 17 years of experience advising senior executives and investment professionals on intellectual property matters. She holds a JD from DePaul University and a BS from the University of Illinois.

After being diagnosed with a rare kidney cancer following the birth of her youngest child, Leah became an active advocate for the kidney cancer community. She brings a valued patient perspective to her work with KidneyCAN, shaped by her commitment to her family, her resilience, and her drive to support others navigating this disease.

Leah lives in Chicago with her husband and four children and enjoys tennis, coaching youth sports, and family travel.

A. ARI HAKIMI, M.D.

DIRECTOR

Ari Hakimi, M.D., is a leading urologic oncologist specializing in kidney cancer. He serves as an Attending Surgeon at Memorial Sloan Kettering Cancer Center and is an Associate Professor of Urology at Weill Cornell Medical College.

Dr. Hakimi earned his medical degree from Albert Einstein College of Medicine and completed his residency in urology at Memorial Sloan Kettering Cancer Center. He then pursued advanced fellowship training in urologic oncology, further refining his expertise in the surgical management of kidney and other genitourinary cancers.

At Memorial Sloan Kettering, Dr. Hakimi is deeply involved in both clinical care and research, with a focus on improving outcomes for patients with kidney cancer. His research explores the molecular and genetic drivers of kidney tumors, helping to advance precision medicine and inform more personalized treatment approaches.

He has contributed extensively to the scientific literature and is actively involved in multidisciplinary efforts to develop innovative therapies for kidney cancer. His work bridges surgical excellence with cutting-edge research to improve patient care.

HANS HAMMERS, M.D., Ph.D.

DIRECTOR

Hans Hammers, M.D., Ph.D., is a nationally and internationally recognized medical oncologist who focuses primarily on kidney cancer. He is a Professor in the Department of Internal Medicine at UT Southwestern Medical Center, and a member of its Division of Hematology and Oncology. He is the inaugural Eugene P. Frenkel, M.D. Scholar in Clinical Medicine.

Originally from Germany, Dr. Hammers received his medical and doctoral degrees from the Medical University of Luebeck. He completed his residency in internal medicine at Johns Hopkins Bayview Medical Center in Baltimore, and then received advanced training through a fellowship program in medical oncology at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University.

Also at Johns Hopkins, Dr. Hammers led the kidney cancer research efforts and played a major role in the development of immunotherapy with immune checkpoint inhibitors in kidney cancer. His work in immunotherapy has been nationally recognized, and he has been the principal investigator on several industry- and investigator-sponsored trials.

Board certified in internal medicine and in medical oncology, he joined the UT Southwestern faculty in 2016.

He is co-leader of clinical research and immunotherapy for the kidney cancer research program and will be continuing his research efforts to develop novel immunotherapies for kidney cancer.

GLENN HOSKIN

DIRECTOR

Glenn is the Executive Vice President of Energy and Natural Resources at Maine Pointe. He is a highly accomplished supply chain executive with 20+ years of international industry and consulting experience across all functional areas of supply chain and operations. He has led supply chain practices at multiple firms, with a focus on delivering significant income statement and balance impacts through cost structure, working capital and fixed asset optimization.

Before his work at Maine Point, Glenn was a Partner/Principal at Ernst & Young, North America Strategic Sourcing and Category Management. Glenn also leads the Central Region Advisory Services for Energy Market, Oil & Gas, Utilities, Diversified Industrial, Consumer Products and Chemicals Clients.

Prior to his career in consulting, Glenn served with the Central Intelligence Agency and the Department of State in Europe and Asia Pacific.

Glenn has a degree in economics from Gordon College and an MBA from Indiana University, Bloomington.

HOWARD MCCLURD

DIRECTOR

Howard McClurd is an 18-year kidney cancer survivor and recent prostate cancer survivor. For over 25 years, he has been a successful owner of multiple businesses in the medical field. Howard currently owns a specialty medical supply company and a “One You Love Home Healthcare” franchise location in the Philadelphia, Pennsylvania, area.

Howard has served on multiple nonprofit boards to help organizations grow and prosper, including “Dragonfly Forest” for children with autism, Down syndrome, persistent asthma, sickle cell disease, and hemophilia. As a fundraiser and supporter for many cancer organizations, he often brings his “Race for a Cure” racecar to charity events to raise money.

Howard focused his work and joined KidneyCAN in 2017 to team up with his cousin Brenda and her husband Ralph Knapp in funding research for a cure. With KidneyCAN, Howard works on medical and pharmaceutical outreach for funding and is a team leader for KidneyCAN’s advocacy efforts.

Dr. Rana McKay | Expert Panelist | Kidney Cancer Town Hall by KidneyCAN

RANA R. MCKAY, M.D.

DIRECTOR

Rana R. McKay, M.D., is a nationally recognized medical oncologist specializing in kidney cancer and other genitourinary malignancies. She serves as a Professor of Medicine at the University of California San Diego and is a physician at UC San Diego Health.

Dr. McKay received her medical degree from the Keck School of Medicine of the University of Southern California. She completed her residency in internal medicine at the University of California Los Angeles, followed by a fellowship in hematology and oncology at Dana-Farber Cancer Institute and Harvard Medical School.

At UC San Diego, Dr. McKay plays a leading role in clinical research, with a focus on developing and advancing novel therapies for kidney cancer. She has been the principal investigator on numerous clinical trials and is widely recognized for her contributions to improving outcomes for patients through innovative treatment approaches.

Her work spans translational and clinical research, including immunotherapy and targeted therapies, and she is actively involved in national and international collaborations to accelerate progress in kidney cancer care.

Board certified in internal medicine and medical oncology, Dr. McKay is committed to delivering personalized, patient-centered care while advancing the field through research and clinical leadership.

STEVEN ZEIGER

DIRECTOR

Steven advises families on strategies to help enhance after tax yields on their investments and assets. He has been published and cited in Trust & Estates Magazine.

As a member of the National Association of Estate Planning Speakers Bureau, he has addressed over fifteen Estate Planning Councils. Steven, guided by the book Blue Ocean Strategies, helps advisors create market niches for their new business development plans.

Steven and his family live in Chappaqua, New York.

He enjoys playing tennis, skiing, and ping pong and traveling with his family. He is currently training for the Dana-Farber Cancer Institute Pan Mass Challenge and MSKCC Cycle For Survival.

Our Team

Debra Beyhan

LEGISLATIVE PATIENT ADVOCATE

Debra Beyhan has served as a volunteer and KidneyCAN’s Legislative Patient Advocate for several years. Deb leads the kidney cancer community of delegates for our advocacy events, including Spring and Fall Advocacy Days and our summer District Days event.

Deb has a deep understanding of the Congressionally Directed Medical Research Programs’ funding process, as well as the impact of Congressional funding on kidney cancer research. She recruits advocates to grow our voice and helps our advocacy team present a strong case to Congress for continued research funding. Deb has also been instrumental in bringing doctors to our advocacy team in 2021.

Debra lives in Atlanta, Georgia.

External Committee Involvement
4 years CDMRP KCRP Consumer Reviewer

Melissa Derr

PROGRAM DIRECTOR

Melissa Derr, our Program Director, brings extensive experience in patient support, fundraising, and advocacy. Her work with the Andy Derr Foundation and KidneyCAN has been instrumental in securing resources for kidney cancer patients, families, and researchers.

Driven by her family’s experience, Melissa is dedicated to advancing research, increasing funding, and improving treatments. Her passion for advocacy began with her father-in-law, Andy Derr, who was diagnosed with kidney cancer at 42. After surgery, he remained cancer-free for over a decade, inspiring Melissa’s mission to fight for a future with better outcomes for all.

After Andy’s passing, Melissa continued her work with the Andy Derr Foundation, but she wanted to expand her impact. In 2021, ADF partnered with KidneyCAN’s Advocacy Days, and Melissa joined her first meetings with lawmakers.

Angie Edwards

OPERATIONS MANAGER

Angie Edwards has served as the Operations Manager for KidneyCAN since 2019.

Angie coordinates KidneyCAN team and event schedules, manages projects and timelines, organizes records and documents, and keeps operations running smoothly. She also facilitates communication between KidneyCAN and partners, sponsors, and the general community.

Though she currently lives in Oreland, Pennsylvania, with her husband, Rob, Angie is a Georgia girl at heart and brings Southern hospitality to the KidneyCAN team.

ADRIAN HAYES

COMMUNICATIONS

Adrian Hayes joined the KidneyCAN team in 2019. She handles KidneyCAN’s communications needs, including the KidneyCAN and KCRS websites, social media channels, content strategy and promotion development, as well as graphic design.

Adrian has a bachelor’s and a master’s degree from the University of Virginia.

Adrian is the owner of Type A Virtual Solutions in Virginia Beach, Virginia, where she lives with her husband Jason and their four children.

SUSAN POTEAT

MEDICAL SCIENCE LIAISON

Susan serves as our liaison with the medical and scientific community. Her 25-year experience as a medical physicist in radiation oncology and her 20-year personal experience as a caregiver and advocate for kidney cancer patients informs her participation as a patient voice in multiple settings. She currently serves as an advocate in multiple settings including Renal Task Force, KCRP Programmatic Panel, and Kidney Cancer Research Consortium.

Since her husband’s diagnosis with kidney cancer in 2007, Susan has served the kidney cancer community as a volunteer patient navigator on SmartPatients.com, particularly in patient education with a special interest in clinical trials. She assists with the organization of the Kidney Cancer Research Summit (KCRS) and coordinates with our medical and scientific advisors on project development and the development of educational content for patients.

External Committee Involvement

  • 2018-2024: NCI Renal Task Force Patient Advocate
  • 2016-2018: DOD CDMRP KCRP Patient Advocate Grant reviewer
  • 2019: FDA training as a Patient advocate for kidney cancer was completed
  • 2019: SPORE Patient Advocate Reviewer
  • 2021: Patient Advocate for NIH Radiation Oncology Working Group, Immunotherapy and Radiation Subgroup
  • 2022-present: MSKCC SPORE External Advisory Board
  • 2020-present: DOD CDMRP KCRP Programmatic Panel
  • 2022-present:  Kidney Cancer Research Consortium External Review Board
  • 2024-present:  NCI Genitourinary Steering Committee (GUSC)

MERYL URANGA

COMMUNITY LIAISON, PATIENT ADVOCACY

Meryl Uranga is a proud almost 9 year kidney cancer survivor. She spent her first professional decade as a radio personality and DJ, and retired from her 30 year Telecom project management career in 2019.

Meryl now focuses on accelerating cures with KidneyCAN as a Community Liaison patient advocacy, legislative patient advocate and SE team lead, and media representative.

External Committee Involvement

  • CDMRP KCRP Consumer Reviewer
  • (Applied for) AACR Scientist Survivor program
  • Various media appearances on behalf of KidneyCAN

Scientific Advisory Board

Latest News

KidneyCAN Visits Congressional Offices

KidneyCAN Program Director, Melissa Derr, is on the Hill today visiting congressional offices before the House Defense Appropriations bill is drafted. We are reminding key offices of our FY27 request: restore funding for the Kidney Cancer Research Program to $50...

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KidneyCAN Advocate Speaks at Congressional Briefing

KidneyCAN advocate, team lead, and US Veteran, Bruce Hill, speaks at a Congressional briefing hosted by CDMRP Director Colonel Hartell. This briefing gives a CDMRP overview, discusses organizational priorities, and highlights research accomplishments. Bruce speaks...

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